The aim of the game is simple. try to guess how correlated the two variables in a scatter plot are. The closer your guess is to the true correlation, the better.
I was in the programming channel of the lesswrong slack this morning (it's a group chat web thing, all are welcome to ask for an invite if you'd like to chat with rationalists in a place that is not the archaic, transient mess that is IRC. (though irc.freenode.net/#lesswrong is not so terrible a place to hang out either, if you're into that))
, and a member expressed difficulty maintaining their interest in programming as a means to the end of earning to give. I've heard it said more than once that you can't teach passion, but I'd always taken that as the empty sputtering of those who simply do not know what passion is or what inspires it, so I decided, since we two have overlapping aesthetics and aspirations, that I would try to articulate my own passion for programming. Maybe it would transfer.
Here's what I wrote, more or less
...So, the problem that most philosophers in academia trip over, get impaled on, and worship for the rest of their careers, is that they're using great clumbering conceptual frameworks that they do not and cannot ever understand, that is, natural language and common-sense reasoning, as it were evolved by a blind, flawed process that has never embarked to write
Why haven't the good people at GiveWell written more about anti-aging research?
According to GiveWell, the AMF can save a life for $3.4e3. Let's say it's a young life with 5e1 years to live. A year is 3.1e7 seconds, so saving a life gives humanity 1.5e9 seconds, or about 5e5 sec/$.
Suppose you could invest $1e6 in medical research to buy a 50-second increase in global life expectancy. Approximating global population as 1e10, this buys humanity 5e11 seconds, or about the same value of 5e5 sec/$.
Buying a 50-second increase in life expectancy for a megabuck seems very doable. In practice, any particular medical innovation wouldn't give 50 seconds to everyone, but instead would give a larger chunk of time (say, a week) to a smaller number of people suffering from a specific condition. But the math could work out the same.
Of course, it could turn out that the cost of extending humanity's aggregate lifespan with medical research is much more than $5e5/sec. But it could also turn out to be much cheaper than that.
ETA: GiveWell has in fact done a lot of research on this theme, thanks to ChristianKl for pointing this out below.
For AMF it's a lot easier to estimate the effect than it is for anti-aging research. GiveWell purposefully started with a focus on interventions for which the can study the effect.
GiveWell writes:
Medical research : As of November 2011, we are just beginning to consider the cause of medical research. Conceptually, we find this cause promising because it is possible that a relatively small amount spent on research and development could result in new disease-fighting technology that could be used to save and improve many lives throughout the world. However, we do not yet have a good sense of whether this cause has a strong track record of turning charitable dollars into lives saved and improved.
You find a bit of data gathering under http://www.givewell.org/node/1339
More recently GiveWell Labs which then was renamed into the Open Philanthropy project will put more emphasis in that direction.
Articles that were written are:
http://blog.givewell.org/2013/12/26/scientific-research-funding/
Why explore scientific research? We expect it to be a difficult and long-term project to gain competence in scientific research funding.
http://blog.givewell.org/2014/01/07/exploring-life-sciences...
Here they found dopamine to encode some superposed error signals about actual and counterfactual reward:
http://www.pnas.org/content/early/2015/11/18/1513619112.abstract
Could that be related to priors and likelihoods?
Significance
...There is an abundance of circumstantial evidence (primarily work in nonhuman animal models) suggesting that dopamine transients serve as experience-dependent learning signals. This report establishes, to our knowledge, the first direct demonstration that subsecond fluctuations in dopamine concentration in the human striatum combin
I wonder if starting a GiveWell-like organization focused on evaluating the cost-effectiveness of anti-aging research would be a more effective way to fund the most effective anti-aging research than earning-to-give. Attracting a Moskovitz-lever funder would allow us to more than completely fund SENS (provisional on SENS still seeming like the best use of funds after more research was done).
Thoughts this week:
Effective Altruism
(1)
All I want for Christmas...is for someone from the effective altruism movement to take the prospect of using sterile-insect techniques and more advanced gene drives against the Tsetse fly seriously. This might control African Sleeping Sickness, a neglected disease, and more importantly, unlock what is largely suspected to be THE keystone cause, according to GiveWell of malnutrition in Africa through an extensive causal pathway. I feel EA's are getting too stuck into causes that were identified early in the movement a...
As a pampered modern person, the worst part of my life is washing dishes. (Or, rinsing dishes and loading the dish washer.) How long before I can buy a robot to automate this for me?
Short papers get cited more often. Should we believe that the correlation is due to causal factors? Should aspriring researchers keep their titels as short as possible?
The science myths that will not die
False beliefs and wishful thinking about the human experience are common. They are hurting people — and holding back science.
The Strangest, Most Spectacular Bridge Collapse (And How We Got It Wrong)
...Bridge building has been bedeviling humans for a long time, probably since the 1st century. That may explain why, even when they can't carry lots of people or things, bridges are particularly good at carrying lots of meaning: breaking, burning, going too far, going nowhere; the bridges between cultures, across generations, the ones we’ll cross when we come to them. To this day, however, the meanings of Gertie's collapse and that unforgettable footage—"among the most dramatic an
Notes on the Oxford IUT workshop by Brian Conrad
...Since he was asked by a variety of people for his thoughts about the workshop, Brian wrote the following summary. He hopes that a non-specialist may also learn something from these notes concerning the present situation. Forthcoming articles in Nature and Quanta on the workshop will be addressed at the general public. This writeup has the following structure:
Background
What has delayed wider understanding of the ideas?
What is Inter-universal Teichmuller Theory (IUTT = IUT)?
What happened at the confe
This is a kind of repost of something I share on the LW slack.
Someone mentioned that "the ability to be accurately arrogant is good". This was my reply:
...One aspect of arrogance is that it is how some competent people with a high self-esteem are perceived to be. I certainly was often perceived as arrogant. At least I got called that way quite often when I was younger and judging from some recent discussions which heavily reflected on that I probably made that impression for most of my life. I didn't and couldn't understand why. I certainly didn
Here's a letter to an editor.
"The Dec. 6 Wonkblog excerpt “Millions and millions of guns” [Outlook] included a graph that showed that U.S. residents own 357 million firearms, up from about 240 million (estimated from the graph) in 1995, for an increase of about 48 percent. The article categorically stated that “[m]ore guns means more gun deaths.” How many more gun deaths were there because of this drastic increase in guns? Using data from the FBI Uniform Crime Reports, total gun murders went from 13,673 in 1995 to 8,454 in 2013 — a decrease in gun dea...
How much should you use LW, and how? Should you consistently read the articles on Main? What about discussion? What about the comments? Or should a more case-by-case system be used?
Does anyone know of some good program for eye training. I would like to try to become a little less near-sighted by straining to make out things which are at the edge of my range of good vision. I know near-sighted means my eyeball is squashed, but I am hoping my brain can fix a bit of the distortion in software. Currently I am doing random printed out eye charts, and I have gotten a bit better over time, but printing out the charts is tedious.
Thoughts this week:
Effective Altruism
(1)
All I want for Christmas...is for someone from the effective altruism movement to take the prospect of using sterile-insect techniques and more advanced gene drives against the Tsetse fly seriously. This might control African Sleeping Sickness, a neglected disease, and more importantly, unlock what is largely suspected to be THE keystone cause, according to GiveWell of malnutrition in Africa through an extensive causal pathway. I feel EA's are getting too stuck into causes that were identified early in the movement and are neglected the virtue of cause neutrality.
(2)
Isn't it time effective altruists matured to using standardised measures of impact on an individual such as the impact on psychological distress. Then, approximated where interventions sat on a scale of magnitude of cummulative K10 scores. They're a simple metric, you can teach NGO/Aid orgs how to understand them quickly and measures of psychological well-being are the 'net result' of individual differences in changes to health and SES.
(3)
Any thoughts on the prospective impact of a documentary about effective altruism? Looks like the best we got are Vaughan's great speeches from effective altruism global and other little to no view YouTube clips, and Singer's TED talk.
(4)
Kidney donation saves 14 QALY. Death organ donation saves perhaps 10 people with donations, that's 140 QALY's. GiveWell gets a QALY for about 80 bucks, so being an organ donor is worth about 80*140=11200 dollars. Upon Googling I found cyronics has a 90 percent chance of success. That sounds wildely optimistic so I'm going to half that and estimate that unintended consequences will kill my (guess) 500 years into my life. So, assuming that extends from a 80 year average lifestyle, I'd have to make 500-80 years of additional life = 420. Maths isn't needed to suggest I'll have a donation capacity and propensity for as if not more effectiveness donation opportunities than GiveWell's in those years. So, cyronics is more altruistic for EA's than organ donors, no?
Update, the lesswrong survey says the probability is 7% at a glance. So that's around 1/15.
420/15 = 28 years. In 28 years I still imagine I'd be able to donate that amount, assuming 10%/y income donation into a trust that actualises upon my death.
Productivity
(1)
I want to contionue to streamline my workflow. Screw SMS, I'm gonna phase out to email alone with Google Voice forwarding on my SMS's to email
Relationships
Anyone on LessWrong wanna get together ha ... ha ...? Just assume the worst traits for me, and don't ask about them. Then just evaluate my writing here as my best trait and make a choice on that ;)
Info diet
Last read with an open mind: Zero to One by Peter Thiel
Take-aways from this one include:
the importance of thinking carefully about marketshare
the value of ‘value-capture’ and thinking like a monopolist to private gains
Last listened to with an open mind: Danger and Play podcast by Mike Cenovich
Take-aways from this one include:
Last watched with an: Mark Freeman (youtube)
Medical malpractice
Australia has the highest rate of medical error in the world according to the World Health Organisation. Counterintuitive as it may seem in Australia there are negligible institutional incentive to fight medical malpractice Instead over the past couple of years, extensive lobbying has taken place by the medical profession for changes to the law for medical negligence in Australia. Medical lobby groups have sought to have the governments legislate what is known as the Bolam test- where the negligence of a doctor is determined solely on the basis of other doctor’s opinions about the doctor’s conduct, regardless of what judges and the courts have to say
From the last article, some other interesting points made:
In a 1999 study reported in the Medical Journal of Australia, it was found that most of health care complainants were not satisfied with either the process or the outcome. Typically they wanted stronger measures taken. Only a few wanted compensation; more wanted acknowledgement of harm done; and most wanted the doctor punished.
Following medical negligence in Australia not every patient sues whenever something goes wrong. Most patients just want the mistake to be acknowledged, and for the doctor to apologise.
Getting a lawyer to deal with medical negligence in Australia is becoming more difficult and a common myth is that lawyers take on ANY case regardless of its merits, in order to make $$$.
The commercial reality is that lawyers only take cases on if they believe there is a good chance of winning i.e if they are meritorious claims. After all, most cases are done on a No Win No Fee basis, so if the lawyer loses, then they won't get paid; there is just no financial incentive in running a frivolous claim.
The government has almost completely done away with legal aid for medical negligence victims. If it wasn't for lawyers taking on the financial risks of running a medical negligence case, most Australian citizens would not be able to afford to pursue their rights.
Looks like a pretty tangly situation with no clear fix
Isn't it time effective altruists matured to using standardised measures of impact on an individual such as the impact on psychological distress.
EA mostly is about using statistics that are already out there.
The K10 scores has questions that are strongly culturally dependent. 1. During the last 30 days, about how often did you feel tired out for no good reason? depends heavily on what people consider to be "good reasons which differes a lot from culture to culture. It might very well be interpreted by some people as: Did you do anything that produced karma that you have to pay of by being tired
If it's worth saying, but not worth its own post (even in Discussion), then it goes here.
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