Sorry if I'm misunderstanding the method, but doesn't it work something like finding strangers who have common genetics by chance?
If so, then 2 jews are more likely to have common genetics than chance, and also more likely to be circumcised. So it would appear that circumcision is genetic, when in fact it's cultural.
It works by finding common genetics up to a limit of relatedness like fourth-cousin level. I think some Jewish groups may be sufficiently inbred/endogamous for long enough periods that it might not be possible to run GCTA with the usual cutoff since they'll all be too related to each other. Population structure beyond that is dealt with by the usual approach of subtracting out 10 or 20 principal components and including them to control for that. This is a bit ad hoc but does work well in GWASes and gets rid of that problem, as indicated by the fact that th...
If it's worth saying, but not worth its own post (even in Discussion), then it goes here.
Notes for future OT posters:
1. Please add the 'open_thread' tag.
2. Check if there is an active Open Thread before posting a new one. (Immediately before; refresh the list-of-threads page before posting.)
3. Open Threads should be posted in Discussion, and not Main.
4. Open Threads should start on Monday, and end on Sunday.