The interviewer accused Eliezer of being religious-like. But if the universe is deterministically moving from state to state then it's just like a computer, a machine that moves predictably from state to state. Therefore it's not religious at all to believe anything in the world (including intelligence) could eventually be reproduced in a computer.
But of course the universe is not like a computer. Everything a computer does until the end of time is implied in it's initial state, the nature of it's CPU, and subsequent inputs. It can never deviate from that course. It can never choose like a human, therefore it can never model a human.
And it's not possible to rationally argue that choice is an illusion because reason uses choice in it's operations. If you use something in the process of arguing against it, you fall in to absurdity. e.g. your proof comes out something like: "I presumed P, pondered Q and R, chose R, reasoned thusly about R vs S, finally choosing S. Therefore choice isn't really choosing."
I appear today on Bloggingheads.tv, in "Science Saturday: Singularity Edition", speaking with John Horgan about the Singularity. I talked too much. This episode needed to be around two hours longer.
One question I fumbled at 62:30 was "What's the strongest opposition you've seen to Singularity ideas?" The basic problem is that nearly everyone who attacks the Singularity is either completely unacquainted with the existing thinking, or they attack Kurzweil, and in any case it's more a collection of disconnected broadsides (often mostly ad hominem) than a coherent criticism. There's no equivalent in Singularity studies of Richard Jones's critique of nanotechnology - which I don't agree with, but at least Jones has read Drexler. People who don't buy the Singularity don't put in the time and hard work to criticize it properly.
What I should have done, though, was interpreted the question more charitably as "What's the strongest opposition to strong AI or transhumanism?" in which case there's Sir Roger Penrose, Jaron Lanier, Leon Kass, and many others. None of these are good arguments - or I would have to accept them! - but at least they are painstakingly crafted arguments, and something like organized opposition.