While these sound good, the rationale for why these are good goals is usually pretty hand wavy (or maybe I just don't understand it).
At some point you just got to start with some values. You can't "justify" all of your values. You got to start somewhere. And there is no "research" that could tell you what values to start with.
Luckily, you already have some core values.
The goals you should pursue are the ones that help you realize those values.
but there are a ton of important questions where I don't even know what the goal is
You seem to think that finding the "right" goals is just like learning any mundane fact about the world. People can't tell you what to want in life like they can explain math to you. It's just something you have to feel out for yourself.
Let me know if I'm miss-reading you.
The next step is to distinguish between terminal and instrumental values, or perhaps we could call them "goals" and "strategies". Which things you want because they feel intrinsically valuable, and which things you want because they seem like a good idea to help you achieve the former.
For example, a goal may be "to be respected by others", and a possible strategy is "get formal education". It may be a bit complicated to disentangle, but imagine something like this:
Someone that asks you "if you 100% knew that people will always respect you, would you still ...
I've learned a lot of ways to make smarter decisions (e.g. by being aware of cognitive biases) by reading LessWrong, but there are a ton of important questions where I don't even know what the goal is, so all those techniques don't really help. For example:
There is a lot of advice out there, e.g. just do what makes you happy, work hard and play hard, family always comes first, treat others the way you would like to be treated, what would Jesus do?, the meaning of life is to find the meaning of life, etc. While these sound good, the rationale for why these are good goals is usually pretty hand wavy (or maybe I just don't understand it).
Are you aware of any good answers, or research into what our goals in life should be? I'm not entirely sure what a good answer would look like, but I could see it being based on biology/evolution (they have good explanations for how we got where we are, maybe they have good explanations for where we should go?), or game theory (they often provide good recommendations on what to do, e.g. in auctions, and nuclear war), or AI research (if you're researching goals for computers, maybe you've got something smart to say about human goals as well), or maybe it's something completely different.
I'm very curious to hear your thoughts!