With respect to Born probabilities, TI is on the level of MWI, it has no derivation for them. Similarly, its ontology is rhetorical rather than rigorous.
A central issue for any zigzag-in-time or retrocausal theory of QM would be vacuum polarization, which was the stumbling block for the most serious effort, by Feynman and Wheeler. But Feynman-Wheeler theory is also where the path integral was born, so TI advocates could say, we just need to go back and finish it properly.
http://www.scottaaronson.com/blog/?p=1103
Eliezer's gung-ho attitude about the realism of the Many Worlds Interpretation always rubbed me the wrong way, especially in the podcast between both him and Scott (around 8:43 in http://bloggingheads.tv/videos/2220). I've seen a similar sentiment expressed before about the MWI sequences. And I say that still believing it to be the most seemingly correct of the available interpretations.
I feel Scott's post does an excellent job grounding it as a possibly correct, and in-principle falsifiable interpretation.