Is there a difference between fighting the hypothetical and recognizing that the hypothetical is badly defined and needs so much unpacking that it's not worth the effort? This falls into the latter category IMO.
"Negative impact on happiness" is far too broad a concept, "theism" is a huge cluster of ideas, and the idea of harm/benefit on different individuals over different timescales has to be part of the decision. Separating these out enough to even know what the choice you're facing is will likely render the excercise pointless.
My gut feel is that if this were unpacked enough to be a scenario that's well-defined enough to really consider, the conundrum would dissolve (or rather, it would be as complicated as the real world but not teach us anything about reality).
Short, speculative, personal answer: there may be individual cases where short-term lies are beneficial to the target in addition to the liar, but they are very unlikely to exist on any subject that has wide-ranging long-term decision impact.
Suppose it is absolutely true that atheism has a negative impact on your happiness and lifespan. Suppose furthermore that you are the first person in your society of relatively happy theists who happened upon the idea of atheism, and moreover found absolute proof of its correctness, and quietly studied its effects on a small group of people kept isolated from the general population, and you discover that it has negative effects on happiness and lifespan. Suppose that it -does- free people from a considerable amount of time wasted - from your perspective as a newfound atheist - in theistic theater.
Would you spread the idea?
This is, in our theoretical society, the emotional equivalent of a nuclear weapon; the group you tested it on is now comparatively crippled with existentialism and doubt, and many are beginning to doubt that the continued existence of human beings is even a good thing. This is, for all intents and purposes, a basilisk, the mere knowledge of which causes its knower severe harm. Is it, in fact, a good idea to go around talking about this revolutionary new idea, which makes everybody who learns it slightly less happy? Would it be a -better- idea to form a secret society to go around talking to bright people likely to discover it themselves to try to keep this new idea quiet?
(Please don't fight the hypothetical here. I know the evidence isn't nearly so perfect that atheism does in fact cause harm, as all the studies I've personally seen which suggest as much have some methodical flaws. This is merely a question of whether "That which can be destroyed by the truth should be" is, in fact, a useful position to take, in view of ideas which may actually be harmful.)