The best we can do is to falsify a theory (as Karl Popper proposed), but beyond that we can never say anything about whether a theory is true.
You don't have to go that road, you can also say: "The map is not the territory" and stop looking for true maps but rather value maps based on accuracy or usefulness.
If it's worth saying, but not worth its own post (even in Discussion), then it goes here.
Notes for future OT posters:
1. Please add the 'open_thread' tag.
2. Check if there is an active Open Thread before posting a new one. (Immediately before; refresh the list-of-threads page before posting.)
3. Open Threads should be posted in Discussion, and not Main.
4. Open Threads should start on Monday, and end on Sunday.