VincentYu comments on Open thread, Jan. 19 - Jan. 25, 2015 - Less Wrong Discussion
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This is a hypothesized explanation for the acute performance-enhancing effects of caffeine that fits well with the Algernon argument, but it is not a conclusive result of the literature. For instance, the following recent review disputes that.
Einöther SJL, Giesbrecht T (2013). Caffeine as an attention enhancer: reviewing existing assumptions. Psychopharmacology, 225:251–74.
Abstract (emphasis mine):
The authors' conclusions:
Note the following conflict of interest: