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Barry_Cotter comments on Open thread, Apr. 01 - Apr. 05, 2015 - Less Wrong Discussion
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It may not be an effective way to help people but it sure as hell helps you up to do it up to three times a year. All hail longevity! I regret I am in a rush so I can't link but I believe RomeoSteverns' post on optimising your health has the references.
This is RomeoSteverns' post on optimising your health. See the section under "blood donation". Note that this advice only applies to males.
In response to that I started donating blood once a year (thus by now twice).