Lumifer comments on Open Thread, Jul. 13 - Jul. 19, 2015 - Less Wrong Discussion
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I think empirically it is. The personality changes in (usually older) men who start taking testosterone (e.g. as injections) are well-documented.
Link?
Google up "testosterone replacement therapy" which will lead you to a bunch of PubMed papers and a variety of internet anecdata. Or see e.g. this.