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MattG comments on Open thread 7th september - 13th september - Less Wrong Discussion
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http://www.examine.com has proven that there's a market for user friendly, layman readable, scientific reviews of subjects where there's a lot of BS. This is also an area that could do significant good by shortening the time between scientific discovery and it's effect on people's decisions.
I've seen quite a few layman readable scientific reviews here on LW, and it seems a great business model for someone who likes that type of research.
Some potential areas for which you could start a website like this: