Open thread, Nov. 23 - Nov. 29, 2015

MrMind

If it's worth saying, but not worth its own post (even in Discussion), then it goes here.

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If it's worth saying, but not worth its own post (even in Discussion), then it goes here.

Notes for future OT posters:

1. Please add the 'open_thread' tag.

2. Check if there is an active Open Thread before posting a new one. (Immediately before; refresh the list-of-threads page before posting.)

3. Open Threads should be posted in Discussion, and not Main.

4. Open Threads should start on Monday, and end on Sunday.

I don't think we learn a lot through the number. It might be that multiple genes are regulated by the same mechanism and turning that mechanism down brings us forward.

Indeed, not only is this only looking at the very broad end results of what is seen to co-vary with age in a regular way completely agnostic to mechanism, it is looking only at gene expression in peripheral blood, one very highly specialized (to the point of being a liquid) tissue type.

0zslastman10y

Yeah it doesn't say much. For one thing I'd say it's just about all of the genes that are differentially expressed, if you look hard enough. Regardless, that doesn't tell us how many of them really matter with respect to the things we care about, how many causal factors are at work, or how difficult it will be to fix. Doesn't rule out a single silver bullet aging cure (though other things probably do)

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