gwern comments on Open Thread, January 4-10, 2016 - Less Wrong Discussion
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We don't know. Since you asked, here's the comment from one of the more recent meta-analyses to discuss dose in connection with all-cause mortality, Autier 2014:
1μg=40IU, so 10μg=400IU, 20μg=800IU, and 1250μg=5000IU.
Personally, I'm not sure I agree. The mechanistic theory and correlations do not predict that 400IU is ideal, it doesn't seem enough to get blood serum levels of 25(OH)D to what seems optimal, and I don't even read Rejnmark the same way: look at the Figure 3 forest plot. To me, this looks like after correcting for Smith's use of D2 rather than D3 (D2 usually performs worse), that there are too few studies using higher doses to make any kind of claim (Table 1; almost all the daily studies use <=20μg), and the studies which we do have tend to point to higher being better within this restricted range of dosages.
That said, I cannot prove that 5k IU is equally or more effective, so if anyone is feeling risk-averse or dubious on that score, they should stick with 800IU doses.