Open Thread April 4 - April 10, 2016

Elo

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If it's worth saying, but not worth its own post (even in Discussion), then it goes here.

Notes for future OT posters:

1. Please add the 'open_thread' tag.

2. Check if there is an active Open Thread before posting a new one. (Immediately before; refresh the list-of-threads page before posting.)

3. Open Threads should be posted in Discussion, and not Main.

4. Open Threads should start on Monday, and end on Sunday.

Good job on the study. I wouldn't call that a low n. I'm guessing you used a power analysis such as this one to calculate the sample size prior to the study, but the results are clearly wildly different from whatever your initial projections were, so the n you calculated prior to the study doesn't tell you all that much. Just eyeballing the covariance in your graph of the cumulative distribution (probability is usually listed on the y axis, btw), you've got a very strong result there. I do think intention-to-treat was the wrong system. I would have excluded all nights where you didn't want to use melatonin from the study, and randomly assigned nights where you were considering melatonin to either treatment or baseline. It looks like correcting for that would have given you even stronger results, however. But I think you went way past the point where more nights would have been of much use. Melatonin just doesn't appear to make much difference for you.