In the Sequence, Eliezer made a strong case for the realist interpretation of QM (neo-Everettian many worlds), based on decoherence and Occam's razor. He then, in another point of the Sequence, tied that problem with interesting questions about anthropic probability (the infamous anthropic trilemma), and that cemented MWI as the preferred way to think about QM here.
On the other hand, I think we are still missing the big picture about quantum mechanics: ER = EPR, categorical quantum mechanics, QBism etc. all points us to interesting unexplored directions.
In the Sequence, Eliezer made a strong case for the realist interpretation of QM (neo-Everettian many worlds), based on decoherence and Occam's razor.
It's tendentious to call MWI the only realistic interpretation.
EY makes a case against CI, which in most circumstances would be a case against anti-realism. However his version of CI is actually OR, another realistic theory. So he never makes a case for realism against irrealism.