The only really big nuclear reactor accident (Chernobyl)
The only? I'd agree that Three Mile Island was a minor case, but Fukushima was definitely severe. There were meltdowns and explosions (chemical, due to the hydrogen the high heat cracked off of the cooling water). It will cost billions over decades to clean it up.
Besides, nuclear plants are over-engineered and have multiple automatic failsafe systems.
Yes, I don't expect this to be an issue in the event of a plague. Fukushima's automated safety systems detected the earthquake and did SCRAM the reactor, but then a freaking tsunami destroyed the backup generators powering the cooling pumps before the fuel had time to cool down. Many Japanese died that day, but that was because of the water, not the uranium.
Nuclear meltdowns are disasters because they are expensive, not because they are deadly. The panic during the ensuing evacuation is probably the most dangerous part.
Fukushima
That was caused by the fourth strongest earthquake in the world in half a century, so it's not something you'd expect to happen particularly often.
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