Well, now I have to link this DC: http://dresdencodak.com/2009/08/06/youre-a-good-man-charlie-darwin-2/
(Interestingly, the author, Robert May, after presenting these quotes, goes onto suggest that "Wilberforce, had he possessed an all-encompassing knowledge of the science of his day, could have won the debate. The Darwin–Wallace theory of evolution, at that time, had three huge problems.")
Not a surprise at all. Most major new paradigms have huge gaping flaws; this is one of the core theses of Paul Feyerabend's brand of philosophy of science in works like Against Method (eg. look at his analyses of major flaws in Galileo).
This is our monthly thread for collecting these little gems and pearls of wisdom, rationality-related quotes you've seen recently, or had stored in your quotesfile for ages, and which might be handy to link to in one of our discussions.