Parable of the flooding mountain range
A mountaineer is hiking in a mountain range. There is a thick fog so he cannot see beyond a few meters. It is raining heavily and so the mountain range is being flooded, the mountaineer has to climb to a high place so he won’t get washed away. He will climb towards the highest point in his sight, and if he sees another higher point he will change his direction towards there. Now the mountaineer is standing on the top of a hill, and to his knowledge every direction is downwards, and there is no higher peak in sight. He sits on the hilltop, anxiously watching the rain and hearing the water raising. The water floods the hill and drowns him, washing his dead body into the abyss. Is he on the highest peak of the mountain range? Unlikely Can he ever get there if he cannot see beyond a few metres? Very unlikely. A band of mountaineers are hiking in a mountain range. There is a thick fog so they cannot see beyond a few meters. It is raining heavily and so the mountain range is being flooded, the mountaineers have to climb to a high place so they won’t get washed away. They elected the most experienced mountaineer as their leader, in the fog he can see a couple metres further than everybody else, and so he is the best guide possible for anyone. The band all followed him onto a hilltop, every direction is downwards so they stayed there, anxiously watching the rain and hearing the raising waters. Until the water floods the hilltop and drowns them, washing their dead bodies into the abyss. This band is functionally the same as a lone mountaineer. A band of mountaineers are hiking in a mountain range. There is a thick fog so they cannot see beyond a few meters. It is raining heavily and so the mountain range is being flooded, the mountaineers have to climb to a high place so they wo
I was thinking of iatrogenic transmissions, yeah (and prions have been a long term psychological fear of mine, too...so I perhaps crawled too much publicly available information about prions to be a normal person)
I wonder if there are any instances of FFI transmitted through the iatrogenic pathway, and whether it is possible to be distinguished from the typical CJD, and whether iatrogenic prions could become a significant issue for healthcare (more instances of prion diseases due to aging population could possibly mean more contaminated medical equipments, and the possible popularisation of brain-computer interface might give us some problems too) given the difficulty of sterilising prions.
Maybe the sample size is too small for us to know.