Another consideration, though maybe not a fundamental one, is that past and future selves are the only beings we know for sure that we have lots of subjunctive dependence with, just from "structural" similarity like calculators from the same factory (to use an example from the TDT paper). Tumblr usr somnilogical elaborated on this a bit, concluding "future selves do help past selves!" An upload is a future self in the way that matters for this conclusion.
Yes, and I did look at something like four of the individual studies of depression, focusing on the ones testing pills so they would be comparable to the Prozac trial. As I said in the post, they all gave me the same impression: I didn't see a difference between the placebo and no-pill groups. So it was surprising to see the summary value of -0.25 SMD. Maybe it's some subtle effect in the studies I looked at which you can see once you aggregate. But maybe it's heterogeneity, and the effect is coming from the studies I didn't look at. As I mentioned in the post, not all of the placebo interventions were pills.
From a quick look on Wikipedia I don't see anything. Except for patients that report side effects from placebo, but of course that could be symptoms that they would have had in any case, which they incorrectly attribute to the placebo.
I don't see how you could get an accurate measure of a nocebo effect from misdiagnoses. I don't think anyone is willing to randomize patients to be misdiagnosed. And if you try to do it observationally, you run into the problem of distinguishing the effects of the misdiagnosis from whatever brought them to the doctor seeking diagnosis.
I took a look at The Secret of Our Success, and saw the study you're describing on page 277. I think you may be misremembering the disease. The data given is for bronchitis, emphysema and asthma (combined into one category). It does mention that similar results hold for cancer and heart attacks.
I took a look at the original paper. They checked 15 diseases, and bronchitis, emphysema and asthma was the only one that was significant after correction for multiple comparisons. I don't agree that the results for cancer and heart attacks are similar. They seem within the range of what you can get from random fluctuations in a list of 15 numbers. The statistical test backs up that impression.
If this is a real difference, I would expect it has something to do with lifestyle changes, rather than stress. However, it's in the opposite direction of what I would expect. That is, I would expect those with a birth year predisposed to lung problems to avoid smoking. I did find some chinese astrology advice to that effect. Therefore they should live longer, when in fact they live shorter. So that doesn't really make sense.
This result seems suspicious to me. First of all because it's just a couple of diseases selected out of a list of mostly non-significant tests, but also because people probably do lots of tests of astrology that they don't publish. I wouldn't bet on it replicating in another population.
It's okay, the post is eight pages long and not super internally consistent, basically because I had to work on Monday and didn't want to edit it. I don't make a post like that expecting everyone to read every paragraph and get a perfectly clear idea of what I'm saying.
Observation of the cosmic microwave background was a simultaneous discovery, according to James Peebles' Nobel lecture. If I'm understanding this right, Bob Dicke's group at Princeton was already looking for the CMB based on a theoretical prediction of it, and were doing experiments to detect it, with relatively primitive equipment, when the Bell Labs publication came out.
"Norman Borlaug’s Green Revolution" seems to give the credit for turning India into a grain exporter solely to hybrid wheat, when rice is just as important to India as wheat.
Yuan Longping, the "father of hybrid rice", is a household name in China, but in English-language sources I only seem to hear about Norman Borlaug, who people call "the father of the Green Revolution" rather than "the father of hybrid wheat", which seems more appropriate. It seems that the way people tell the story of the Green Revolution has as much to do with national pride as the facts.
I don't think this affects your point too much, although it may affect your estimate of how much change to the world you can expect from one person's individual choices. It's not just that if Norman Borlaug had died in a car accident hybrid wheat may still have been developed, but also that if nobody developed hybrid wheat, there would still have been a Green Revolution in India's rice farming.
Green fluorescent protein (GFP). A curiosity-driven marine biology project (how do jellyfish produce light?), that was later adapted into an important and widely used tool in cell biology. You splice the GFP gene onto another gene, and you've effectively got a fluorescent tag so you can see where the protein product is in the cell.
Jellyfish luminescence wasn't exactly a hot field, I don't know of any near-independent discoveries of GFP. However, when people were looking for protein markers visible under a microscope, multiple labs tried GFP simultaneously, so it was determined by that point. If GFP hadn't been discovered, would they have done marine biology as a subtask, or just used their next best option?
Fun fact: The guy who discovered GFP was living near Nagasaki when it was bombed. So we can consider the hypothetical where he was visiting the city that day.
I like it a lot. I'm mainly a tumblr usr, and on tumblr we're all worried about the site being shut down because it doesn't make any money. I love having LessWrong as a place for writing up my thoughts more carefully than I would on tumblr, and it also feels like a sort of insurance policy if tumblr goes under, since LessWrong seems to be able to maintain performance and usability with a small team. The mods seem active enough that they frontpage my posts pretty quickly, which helps connect them with an audience that's not already familiar with me, whereas on tumblr I haven't gotten any readers through the tag system in years and I'm coasting on inertia from the followers I already have.
My guesses at what the spoiler was going to be:
Ten non-independent trials, a 10% chance each (in the prior state of knowledge, not conditional on previous results,), and only one trial can succeed. You satisfy these conditions with something like "I hid a ball in one of ten boxes", and the chance really is 100% that one is a "success".
Regardless of whether the trials are independent, the maximum probability that at least one is a success is the sum of the probabilities per trial. In this case that doesn't yield a useful bound because we already know probabilities are below 100%, but in general it's useful.
Yeah, it's cool that "I did n trials, with a 1/n chance each, so the probability of at least one success is... " does have a general answer, even if it's not 100%. Just noting that it's not the only small modification of the title yielding a useful and interesting correct statement.
The ones that came to my mind still involved the sum of the per-trial probabilities. If it was clear that we were looking for something preserving the "n trials with 1/n chance", rather than the summation, I think it would have been more obvious where you're going with this.