So there's this blog called Bad Science, consisting mostly of the articles that medical doctor Ben Goldacre writes for the Guardian. It's about pseudoscience, medicine and medical research. And also awesome.
The recent article was a wonderful bit of emotional whiplash, and is about as subject I think is useful to keep in mind when contemplating research. But really, I recommend reading everything.
http://www.badscience.net/2011/05/existential-angst-about-the-bigger-picture/
Also, the second-most-recent article, which should appeal to LW-types:
http://www.badscience.net/2011/05/we-should-so-blatantly-do-more-randomised-trials-on-policy/
I've wondered how I found Overcoming Bias. I've determined the approximate date I found it from a facebook post I made, but I don't remember how I found it. It could have been from Bad Science.