So there's this blog called Bad Science, consisting mostly of the articles that medical doctor Ben Goldacre writes for the Guardian. It's about pseudoscience, medicine and medical research. And also awesome.
The recent article was a wonderful bit of emotional whiplash, and is about as subject I think is useful to keep in mind when contemplating research. But really, I recommend reading everything.
http://www.badscience.net/2011/05/existential-angst-about-the-bigger-picture/
Also, the second-most-recent article, which should appeal to LW-types:
http://www.badscience.net/2011/05/we-should-so-blatantly-do-more-randomised-trials-on-policy/
I put the randomized-trials-for-policy thing on facebook earlier today. I love that idea. It is one of those obvious-to-me ideas that I once I had it, I couldn't believe that we weren't doing it routinely. As if people weren't thinking or something. You want to know whether something works? Try it and find out.
I had a similar feeling when I found out about homosexuality in ancient greece. When I was a kid: Many cultures are weird about homosexuality? Oh, it must be a new thing. What? It has been a well-known, standard minority fraction of human sexuality for thousands of years?
Indeed, but the way people think about sexuality and "sexual orientation" has changed a lot.