A few examples (in approximately increasing order of controversy):
If you proceed anyway...
- Identify knowledge that may be dangerous. Forewarned is forearmed.
- Try to cut dangerous knowledge out of your decision network. Don’t let it influence other beliefs or your actions without your conscious awareness. You can’t succeed completely at this, but it might help.
- Deliberately lower dangerous priors, by acknowledging the possibility that your brain is contaminating your reasoning and then overcompensating, because you know that you’re still too overconfident.
- Spend a disproportionate amount of time seeking contradictory evidence. If believing something could have a great cost to your values, make a commensurately great effort to be right.
- Just don’t do it. It’s not worth it. And if I found out, I’d have to figure out where you live, track you down, and kill you.
It's not obvious that knowing more always makes us better off — because the landscape of rationality is not smooth.
The quote in Eliezer's site stating that "That which can be destroyed by the truth should be." sounded to me too strong a claim from the very first time I read it. Many people cultivate falsehoods or use blinkers that are absolutely necessary to the preservation of their sanity (sic), and removing them could terribly jeopardize their adaptability to the environment. It could literally kill them.