You're smart, want to help the world and are willing to work hard. You have no serious ties such as children or a marriage that would prevent you from making serious changes to your life, and you are willing to place others needs ahead of your own hedonistic desires. Given this, what should you do?
Should you aim to get involved personally with causes you feel passionately about? You can have greater control over your contribution if you do this, but can you achieve the most good in this way? Should you operate at a meta-level, such as by trying to convince other people to change their charitable giving, attempting to influence government policy, or by raising awareness of existential risks, or should you try and directly tackle the problems facing the world -- such as by donating money yourself, or by tackling open problems in friendly AI?
Once you've figured out what to do, you still have to find a way to support yourself, and fund any organizations or projects you wish to support. You could work for an existing organization active in the area that you are interested in - bearing in mind that ones contribution will only be the benefit of hiring you rather than the next-best guy. Or you could work in a completely unrelated job, and work part-time on the cause you are interested in; this is a route followed by many open source developers, e.g. the prolific Fabrice Bellard. Alternatively, you could aim to earn as much money as possible, and use this money to fund causes or projects you are interested in; this is the route followed by Jeff Hawkins, who founded Palm, Inc. in order to fund AI and neuroscience research, as well as notable philantropists such as Bill Gates and Warren Buffet.
The problem is a simple one: how should one lead ones life in order to maximize the positive impact it has on others? There is an ample amount of data to draw from, such as charity rankings by GiveWell, salary data and personal experience. If rationality has any real-world benefits, then a discussion amongst rationalists should make it possible for substantially better decisions to be made than would otherwise be the case.
References
Existential Risk Reduction Careers Network
Well, I'm new here, but I thought I might as well just try it. As far as I can tell, a large segment of LessWrong readers are highly interested in philanthropy, especially existential risk reduction. Given this, there seems to have been surprisingly little discussion as to how to best lead ones life to maximize its positive impact.
Whilst there has been some discussion with regard to selecting between charities, I have seen almost no discussion on choosing between careers, or on how to structure ones life more generally. If the type of rationality taught on this site is to be widely applicable, then it should be able to be applied to such situations successfully.
Whilst obviously these choices are highly individual, I nevertheless think that a group effort should be able to shed some light on the problem. In particular, the standard to beat is quite low -- most people have only very limited knowledge of the careers they go into, and make their decision with only limited analysis. It is even rarer for people to seriously consider what actions they can do to maximise the impact they have on the world, although many people choose careers nominally in order to help people.
Whilst I don't want this post to be about myself, here are a few details about myself: I'm just about to enter university (the university is generally considered to be somewhere amongst the top 10 in the world, and is certainly in the top 4 in my country, the UK) to read Mathematics. I believe that, given my aptitudes, I am best able to make a positive impact on the world by attempting to maximize the money I earn, and donating that. I am undecided between existential risk reduction and more ordinary causes. I don't subscribe to any formal moral system, but my feelings are quite closely aligned with preference utilitarianism. I'm unsure on how much money I should donate, but feel that in the long term I should certainly aim to donate any money I earn whose consumption would not serve to further increase my happiness. If anyone wants more details about my personal situation, feel free to PM me.
Not sure if you've already seen them, but here are a few posts that might be relevant: