All of Maloew's Comments + Replies

Maloew20

Are the new songs going to be posted to youtube/spotify, or should I be downloading them?

Maloew32

Very late followup question: how much additional effort do you think would be neccessary to try to do this for something like stamina/energy? It seems like some people (eg. Eliezer) are bottlenecked more on that than intelligence, and just in general alignment researchers having more energy than their capabilities counterparts seems very useful.

Maloew20

Instead, the U.S. government will do what it has done every time it’s been convinced of the importance of a powerful new technology in the past hundred years: it will drive research and development for military purposes.

I wonder if there is an actual path to alignment-pilling the US government by framing it as a race to solve alignment? That would get them to make military projects focused on aligning AI as quickly as possible, rather than building a hostile god. It also seems like a fairly defensible position politically, with everything being a struggle ... (read more)

Maloew40

It seems plausible to me that some portion of iq-enhancing genes work through pathways outside the brain (blood flow, faster metabolism, nutrient delivery, stimulant-like effects, etc.). If that is the case and even just a small portion of the edits don't need to make it to the brain, couldn't you get huge iq increases without ever crossing the blood-brain barrier?

If timelines are short, it seems worthwhile to do that first and use the gains to bootstrap from there. Would that give significant returns fast enough to be worth doing? Is this something you're already trying to do?

5GeneSmith
It's a good question. This question is hard to answer because we don't have great data on which genes matter in which tissues. But we do have decent proxies; for example we have OK RNA sequencing data from different bodily tissues, and we could probably use that to figure out in which tissues proteins associated with genetic variants known to affect intelligence are most heavily expressed. I haven't thought this to be a huge priority yet because some early data I saw indicated that most of the genetic variants acted primarily through the brain. And given that we probably couldn't yet raise IQ more than a standard deviation even if we had both great brain delivery and better gene editors, it just didn't seem like a high priority yet.