I'm going to take your question in the simple sense that first occurs to me, which is something like "dualism is false, and mysterious quantum effects are unnecessary. ordinary molecular chemistry only."

In that case, my probability approaches 1 that ordinary molecular chemistry is 100% sufficient to describe a system that implements reasoning and creative thought, and - heck - experiences consciousness. However, I also think that explaining how will require abstractions that are probably not yet well-understood.