Given a specific set of inputs/outputs (i.e. the virtual reality of existing as a human in a world with consistent computers, pencils and paper, teachers, students, etc.), and assuming that I intuitively understand what a "substrate of neurons" is, extremely certain (see ciphergoth).

Without a set of inputs or outputs, the question is a tree falling in a forest. A Turing machine doesn't perform computation if it doesn't have inputs.