pdf23ds comments on A survey of anti-cryonics writing - Less Wrong
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I forget who brought this up--maybe zero_call? jhrandom?--but I think a good question is "How quickly does brain information decay (e.g. due to autolysis) after the heart stops and before preservative measures are taken?" If the answer is "very quickly" then cryonics in non-terminal-illness cases becomes much less effective.
I came across a few cites supporting the "quite a bit" answer in the "Cold War" article at Alcor (linked elsewhere on this thread).
There's more at the link.