Personally I run Rosetta@home because, based on my research, it could be more useful to designing new proteins and computationally predicting the function of proteins. Folding seems to be more about understanding how they proteins fold, which can help with some diseases, but isn't nearly the game changing that in silico design and shape prediction would be.

I also think that the SENS Foundation (Aubrey de Grey & co) have some ties to Rosetta, and might use it in the future to design some proteins.

I'm a member of the Lifeboat Foundation team: http://lifeboat.com/ex/rosetta.home

But we could also create a Less Wrong team if there's enough interest.