calcsam comments on Safety can be dangerous - Less Wrong

4 Post author: PhilGoetz 07 September 2011 05:24AM

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Comment author: calcsam 07 September 2011 05:39:23AM 13 points [-]

Also, this is technically not correct:

The FDA is supposed to approve new drugs and procedures if the expected benefits outweigh the expected costs. If they actually did this, the number of people saved by new drugs would be roughly equal to the number killed by them

Actually, if the FDA really did this the marginal -- in this case, most-dangerous -- drug approved should kill as many people as it save. But since every drug before that would save more people as it killed, on net there should be more people saved than killed.

Comment author: PhilGoetz 07 September 2011 05:51:09AM *  5 points [-]

Right - I just logged in to try to fix this, after realizing that if what I originally wrote were true, drugs would have net zero benefit.

(An additional complication is that approval of a good drug gives continued benefits indefinitely, while approval of a bad drug does not give continued costs - its badness is found out and it is taken off the market.)

Comment author: DanielLC 07 September 2011 11:33:58PM 0 points [-]

A lot of this good drug stuff seems to be drugs that are taking a long time to pass, but eventually will. These can be compared simply with the bad drugs.

Comment author: Solvent 10 September 2011 01:51:04AM 1 point [-]

Yay for marginal cost does not equal average cost!