This has some problems- fundamentally the length scale probed is inversely proportional to the energy required, which means increasing the resolution increases the damage done by scanning.
We seem to have very different assumptions here. I am assuming you can get up to the molecule and gently wave a tiny molecular probe in its direction, if required. I am not assuming that you are trying to use high-energy photons to photograph it.
You also still seem to be use a lot of functional-damage words like "destroying" which is why I don't trust your or kalla724's intuitions relative to the intuitions of other scientists with domain knowledge of neuroscience who use the language of information theory when assessing cryonic feasibility. If somebody is thinking in terms of functional damage (it doesn't restart when you reboot it, oh my gosh we changed the conformation look at that damage it can't play its functional role in the cell anymore!) then their intuitions don't bear very well on the real question of many-to-one mapping.
What does the vitrification solution actually do that's supposed to irreversibly map things, does anyone actually know? The fact that a cell can survive with a membrane, at all, considering the many different molecules inside it, imply that most molecules don't functionally damage most other molecules most of the time, never mind performing irreversible mappings on them. But then this is reasoning over molecules that may be of a different type then vitrificants. At the opposite extreme, I'd expect introducing hydrochloric acid into the brain to be quite destructive.
We seem to have very different assumptions here. I am assuming you can get up to the molecule and gently wave a tiny molecular probe in its direction, if required. I am not assuming that you are trying to use high-energy photons to photograph it.
How are you imaging this works? I'm aware of chemistry that would allow you to say there are X whatever proteins, and Y such-and-such enzymes,etc, but such chemical processes I don't think are good enough for the sort of geometric reconstruction needed. Its not obvious to me that a molecular probe of the type ...
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