Given the seemingly high interest I'm considering researching a full post on this. However, going just off what I remember from psyc classes the short answer is we don't know and suspect that you can't alter them much, at least not without doing something drastic. That said, putting yourself in social groups were the desired trait is common/expected looks relatively promising. Additionally, it may be possible to change your behavior in ways that emulate the effects of a big five change without technically changing your personality. In particular the Getting Things Done I learned from CfAR is supposed to boost your effective conscientiousness, and I have observed that to kinda be the case since I adopted it.
This thread is another experiment roughly in the vein of the Boring Advice Repository and the Solved Problems Repository.
There are some topics I'd like to see more LW posts on, but I feel underqualified to post about them relative to my estimate of the most qualified LWer on the topic. I would guess that I am not the only one. I would further guess that there are some LWers who are really knowledgeable about various topics and might like to write about one of them but are unsure which one to choose.
If my guesses are right, these people should be made aware of each other. In this thread, please comment with a request for a LW post (Discussion or Main) on a particular topic. Please upvote such a comment if you would also like to see such a post, and comment on such a comment if you plan on writing such a post. If you leave a writing-plan comment, please edit it once you actually write the post and link to the post so as to avoid duplication of effort in the future.
Let's see what happens!
Edit: it just occurred to me that it might also be reasonable to comment indicating what topics you'd be interested in writing about and then asking people to tell you which ones they'd like you to write about the most. So try that too!