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RomeoStevens comments on Lifestyle interventions to increase longevity - Less Wrong

120 Post author: RomeoStevens 28 February 2014 06:28AM

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Comment author: RomeoStevens 27 February 2014 11:00:38PM 3 points [-]

mean decrease in systolic pressure over 8 studies of 16mm Hg kicks the crap out of a lot of interventions, including some prescription ones.

Comment author: PeterDonis 01 March 2014 04:09:55AM 0 points [-]

Are there any theories about the mechanism involved here? I've done a fair bit of Googling about this but haven't found any discussion of underlying mechanisms, only the statistics. I know that CoQ10 is critical in the metabolic cycle that produces ATP, and therefore is involved in energy production everywhere in the body; but I'm not sure how to get from that to the specific result of lowering blood pressure (rather than something more general like "feel more energetic").

Comment author: RomeoStevens 01 March 2014 08:06:28AM 0 points [-]

The fact that blood pressure is an independent predictor of mortality would imply it affects, and is most likely affected by, a lot of metabolic processes.