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RomeoStevens comments on Lifestyle interventions to increase longevity - Less Wrong

121 Post author: RomeoStevens 28 February 2014 06:28AM

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Comment author: RomeoStevens 27 February 2014 11:02:12PM *  2 points [-]

We're going to be replacing our current sunflower seeds with high oleic acid versions which will bring us down to under 5% of calories from PUFA.

Do you have a jailbroken version of that study anywhere? That's a really large effect, and the best evidence against PUFA yet if true.

Comment author: Mqrius 03 March 2014 12:52:37PM *  1 point [-]

The maximum total energy from PUFA has been a discussion point with DIY Soylent makers as well. The final consensus was that it should definitely be below 10%, and possibly below 4%. The 4% figure comes from The perfect health diet, which uses this as a source:

Angela Liou Y, Innis SM. Dietary linoleic acid has no effect on arachidonic acid, but increases n-6 eicosadienoic acid, and lowers dihomo-gamma-linolenic and eicosapentaenoic acid in plasma of adult men. Prostaglandins, Leukotrienes and Essential Fatty Acids 2009 Apr;80(4):201–6, http://pmid.us/19356914.

I've also got a copy hosted at http://forecast.student.utwente.nl/Lesswrong/ but only download that if your university or company legally gives you access to Elsevier content.

For the discussion and links to other relevant papers, see http://discourse.soylent.me/t/optimal-micronutrient-ratios/5049/52 and further posts

For my Soylent, I ended up getting most fats from macadamia oil (mostly Omega-9 aka MUFA) and MCT oil (Medium-chain saturated fat), since they don't have any negative effects associated with them. Correct me if I'm wrong.

Comment author: Mqrius 03 March 2014 12:35:52PM 1 point [-]

My university has access to the paper. I've got it hosted on my server, but you're only allowed to download it if you have legal access through your university as well. If you have legal access, feel free to click this link:

http://forecast.student.utwente.nl/Lesswrong/The%20importance%20of%20the%20ratio%20of%20omega-6%20omega-3%20essential%20fatty%20acids.pdf

Comment author: TylerJay 28 February 2014 03:34:26AM 1 point [-]

I don't, unfortunately. I thought it looked really high as well. The wording of the abstract seems to indicate that it was an observational/epidemiological study, not an RCT, but you can never really tell from the abstracts.