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Lumifer comments on Open Thread, Aug. 8 - Aug 14. 2016 - Less Wrong
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Presumably this is the kind of thing that is fixable by widespread genetic technologies. Once you can identify and/or fix problematic zygotes, the problem disappears.
Or just straight-up medical cures and treatments.
Also, I have my own medical problems that cause me suffering, but I would still rather be alive than not.