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James_Miller comments on General-Purpose Questions Thread - Less Wrong Discussion
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I know that negative prescription drug interactions are a big deal. Should I be worried about negative interactions among legal supplements I take like Coq10, Vit D, glucosamine, curcumin, desiccated liver, Bacopa Monnieri, or NAC?
One thing I do sometimes is search for the name of 2 different supplements on Amazon and see if I can find a commercial stack where they appear together, then check for 1 star reviews of the stack that describe a negative interaction. (This works best for stacking supplements that have similar purposes, e.g. if you're taking 2 sleep aid supplements at once, it's plausible that they both appear in a commercial stack that someone put together.)
I don't know about "worried", but it would be a good idea to be aware of interactions between things you're taking (and eating). Some are synergetic, some are antagonists.
There are software programs that have databases of drug and supplement interactions. Also, pharmacists tend to know more about these things than doctors. So, you could find a database and search it, and/or ask a pharmacist. There isn't as much information available on supplements as there is about drugs, so it's hard to answer the question with a lot of certainty.