I am curious to see what would be the results of the new Gemini 2.5 pro on internal benchmarks.

I don't think ketamine neurotoxicity is a thing. Ketamine is actually closer to be a neuroprotector. 

The tech stack has shifted almost entirely to whatever there was the most data on; Python and Javascript/Typescript are in, almost everything else is out.

I think AI agents will actually prefer strongly typed languages because they provide more feedback. Working with TypeScript, Python and Rust, while a year ago the first two were clearly winning in terms of AI productivity boost, nowadays I find Cursor Agent making fewer mistakes with Rust.

I think you might find this paper relevant/interesting: https://aidantr.github.io/files/AI_innovation.pdf

TL;DR: Research on LLM productivity impacts in material disocery.

Main takeaways:

• Significant productivity improvement overall
• Mostly at idea generation phase
• Top performers benefit much more (because they can evaluate AI's ideas well)
• Mild decrease in job satisfaction (AI automates most interesting parts, impact partly counterbalanced by improved productivity)

I would like to note that this dataset is not as hard as it might look like. Humans performed not so well because there is a strict time limit, I don't remember exactly but it was something like 1 hour for 25 tasks (and IIRC the medalist only made arithmetic errors). I am pretty sure any IMO gold medailst would typically score 100% given (say) 3 hours.

Nevertheless, it's very impressive, and AIMO results are even more impressive in my opinion.

Thanks, I think I understand your concern well now.

I am generally positive about the potential of prediction markets if we will somehow resolve the legal problems (which seems unrealistic in the short term but realistic in the medium term). 

Here is my perspective on "why should a normie who is somewhat risk-averse, don't enjoy wagering for its own sake, and doesn't care about the information externalities, engage with prediction markets"

First, let me try to tackle the question at face value:

1. "A normie" can describe a large social group, but it's too general to describe a single person. You can be a normie, but maybe you work at a Toyota dealership. Maybe you just accidentally overheard that the head of your department was talking on the phone and said that recently there were major problems with hydrogen cars which are likely to delay deployment by a few years. If there is a prediction market for hydrogen cars, you can bet and win (or at least you can think that you will win). It's relatively common among normies to think along the lines "I bought a Toyota car and it's amazing, I will buy Toyota stock and it will make me rich". Of course, such thinking is usually invalid, Toyota's quality is probably already priced in, so it's a toss of a coin if it will overperform the broader market or not. Overall, it's probably not a bad idea to buy Toyota stock, but some people do it not because it's an ok idea but because they think it's an amazing idea. I expect the same dynamics to play in prediction markets.
2. Even if you don't enjoy "wagering for its own sake", prediction markets can be more than mere wagering.  Although it's a bit similar in spirit, gamification is applicable to prediction markets, for example, Manifold is doing it pretty successfully (from my perspective as an active user, it's quite addictive) although it hasn't led to substantial user growth yet. Even the wagering itself can be different -- you can bet "all on black" because you desperately need money and it's your only chance, you can be drawn by the dopamine-driving experience of the slots, you can believe in your team and bet as kind of confirmation of your belief, you can make a bet to make watching the game more interesting. There are many aspects of gambling which have a wide appeal, and many of them are applicable to prediction markets.

Second, I am not sure it has to be a thing for the masses. In general, normies usually don't have much valuable information, so why would we want them to participate? Of course, it will attract professionals who will correct mispricings and make money but ordinary people losing money is a negative externality which can even outweigh the positive ones.

I consider myself at least a semi-professional market participant. I bet on Manifold and use Metaculus a lot for a few years. I used Polymarket before but don't do it anymore and resort to funny money ones despite they have problems (and of course can't make me money).

Why I am not using Polymarket anymore:

1. As a real market should be, it's far from trivial to make money on Polymarket. Despite that fact, I do (perhaps incorrectly) believe that my bets would be +EV. However, I don't believe that I can be much better than random, so I don't find it to be more profitable than investing in something else. However, if I could bet with "my favourite asset" it would become profitable for me (at least in my eyes, which is all that matters) and I would use it.
2. There are not enough interesting markets, mostly politics or sports. Which is mostly caused by the legal situation. Even Polymarket, a grey-area crypto-based market is very limited by that. PredictIt is even worse. Even if I am wrong here and it's not the reason, still, there will be definitely more platforms which would experiment more if it was legal in the U.S.
3. The user experience is (or at least was) not great. Again, I believe it's mostly caused by legal problems, it's hard to raise money to improve your product if it's not legal.

I do agree with your point, definitely "internalize the positive information externalities generated by them" is something which prediction markets should aspire to, an important (and interesting!) problem.

However, I don't believe it's essential for "making prediction markets sustainably large" unless we have a very different understanding of "sustainably large". I am confident that it would be possible to achieve 1% of the global gambling market which would be billions of revenue and a lot of utility. It even seems to be a modest goal, given that it's a serious instrument. But unfortunately, prediction markets are "basically regulated out of existence" :(

Sidenote on funny money market problems:

Metaculus's problem is that it's not a market at all. Perhaps it's a correct decision but makes it boring, less competitive and less accurate (there are many caveats here, probably making Metaculus a market right now would make it less accurate, but from the highest-level perspective markets are a better mechanism).

Manifold's problem is that serious markets draw serious people and unserious markets draw unserious people. As a result, serious markets are significantly more accurately priced which disincentivises competitive users to participate in them.  That kinda defies the whole point. And also, perhaps even more importantly, users are not engaged enough (because they don't have money at stake) so winning at Manifold is mostly information arbitrage which is tedious and unfulfilling.

Good to know :)

I do agree that subsidies run into a tragedy-of-commons scenario. So despite subsidies are beneficial, they are not sufficient.

But do you find my solution to be satisfactory?

I thought about it a lot, I even seriously considered launching my own prediction market and wrote some code for it. I strongly believe that simply allowing the usage of other assets solves most of the practical problems, so I would be happy to hear any concerns or further clarify my point.

Or another, perhaps easier solution (I updated my original answer):  just allow the market company/protocol to invest the money which are "locked" until resolution to some profit generating strategy and share the profit with users. Of course, it should be diversified, both in terms of investment portfolio and across individual markets (users get the same annual rate of return, no matter what particular thing they bet on). It has some advantages and disadvantages, but I think it's a more clear-cut solution.

Isn't this just changing the denominator without changing the zero- or negative-sum nature?

I feel like you are mixing two problems here: an ethical problem and a practical problem. UPD: on second thought, maybe you just meant the second problem, but still I think my response would be clearer by considering them separately.

The ethical problem is that it looks like prediction markets do not generate income, thus they are not useful and shouldn't be endorsed, they don't differ much from gambling. 

While it's true that they don't generate income and are zero-sum games in a strictly monetary sense, they do generate positive externalities. For example, there could be a prediction market about an increase of <insert a metric here> after implementing some policy.  The market will allow us to estimate the policy efficiently and make better decisions. Therefore, the market will be positive-sum because of the "better judgement" externality.

The practical problem is that the zero-sum monetary nature of prediction markets disincentives participation (especially in year+ long markets) because on average it's more profitable to invest in something else (e.g. S&P 500). It can be solved by allowing to bet other assets, so people would bet their S&P 500 shares and on average get the same expected value, so it will be not disincentivising anymore.

Also, there are many cases where positive externalities can be beneficial for some particular entity. For example, an investment company may want to know about the risk of a war in a particular country to decide if they want to invest in the country or not. In such cases, the company can provide rewards for market participants and make it a positive-sum game for them even from the monetary perspective.

This approach is beneficial and used in practice, however, it is not always applicable and also can be combined with other approaches.

Additionally, I would like to note that there is no difference between ETH and "giving a loan to a business" from a mechanism design perspective, you could tokenize your loan (and it's not crypto-related, you could use traditional finance as well, I am just not sure what "traditional" word fits here) and use the tokenized loan to bet at the prediction market.

but once all the markets resolve, the total wealth would still be $1M, right

Yes, the total amount will still be the same. However, your money will not be locked during the duration of the market, so you will be able to use it to do something else, be it buying a nice home or giving a loan to a real company. 

Of course, not all your money will be unlocked and probably not immediately, but it doesn't change much. Even if only 1% will be unlocked and only in certain conditions, it's still an improvement.

Also, I encourage you to look at it from another perspective:

What problem do we have? Users don't want to use prediction markets.

Surely, they would be more interested if they had free loans (of course they are not going to be actually free, but they can be much cheaper than ordinary uncollateralized loans). 

Meta-comment: it's very common in finance to put money through multiple stages. Instead of just buying stock, you could buy stock, then use it as collateral to get a loan, then buy a house on this loan, rent it to somebody, sell the rent contract and use the proceeds to short the original stock to get into a delta-neutral position. Risks multiply after each stage, so it should be done carefully and responsibly. Sometimes the house of cards crumbles, but it's not a bad strategy per se.

Why does it have to be "safe enough"? If all market participants agree to bet using the same asset, it can bear any degree of risk. 

I think I should have said that a good prediction market allows users to choose what asset will a particular "pair" use. It will cause a liquidity split which is also a problem, but it's also manageable and, in my opinion, it would be much closer to an imaginary perfect solution than "bet only USD". 

I am not sure I understand your second sentence, but my guess is that this problem will also go away if each market "pair" uses a single (but customizable) asset. If I got it wrong, could you please clarify?