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Not necessarily. For all we know, we might not need to simulate a human brain on an atomic level to get accurate results. Simulating a brain on a neuron level might be sufficient.
Even if you approximate each neuron to a neural network node (which is probably not good enough for a WBE), we still don't have enough processing power to do a WBE in close to real time. Not even close. We're many orders of magnitude off even with the fastest supercomputers. And each biological neuron is much more complex than a neural node in function not just in structure.