Eudoxia
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Eudoxia has not written any posts yet.
Is there anything else you would recommend be discussed before I make that initial payment and set the ball in motion?
Sure, the fact that Ben Best experimented on a patient, ruining his perfusion (Emphasis mine):
... (read more)My dear friend and mentor Curtis Henderson was little more than straight frozen because CI President Ben Best had this idea that adding polyethylene glycol to the CPA solution would inhibit edema. Now the thing is, Ben had been told by his own researchers that PEG was incompatible with DMSO containing solutions, and resulted in gel formation. Nevertheless, he decided he would try this out on Curtis Henderson. He did NOT do any bench experiments, or do test
This would be a useful inclusion in a will. For example, add provisions and funds to transport you to another facility should the one you are in fail, and to another if the second is not available, ad infinitum until permafrost interment.
Eric DeMar did something similar in his will, to ensure his parents (Who'd been cryopreserved by Trans Time in the seventies) would be transported to the CI facilities. A very good choice, considering Trans Time's policies.
A separate decision tree may be included to cover alternatives to cryonics, if the entire cryonics decision tree is exhausted of possibilities: Brain-only chemopreservation as the first alternative, high-temperature vitrification as the second, and so on and on until you decide to simply have your body cremated.
As long as you recognize that clotting is a different process. =)
Of course.
It's been a few years since I studied this, but as far as I know, the physiological significance of rouleaux (including whether they block blood vessels) is unknown - don't forget that they're in equilibrium with the non-rouleaux form.
I wouldn't know, but Mike Darwin says they are harmful:
[...] irregular aggregation of RBCs rouleaux formation has a profound negative impact on perfusion.
I've never heard of rouleaux having a role in blood clotting
They block blood vessels and prevent perfusion, which is why it's equivalent to clotting.
Blood clotting is not caused by red blood cells but by platelets.
I thought ischemic tissue caused RBCs to form Rouleaux complexes. Even without RBC's, ischemia causes plenty of changes that have effects functionally equivalent to clotting: Swelling of myocytes and the endothelium, subsarcolemmal and endothelial blebs, et cetera.
I suppose another option would be to suggest that the patient to start taking anticoagulants before death. I'm not sure whether that would have legal implications though.
This is certainly helpful and doesn't seem to have been done in past patients, but we're mostly talking about unexpected settings here, where no standby is available. I don't think it has any legal implications, at least the Best's article doesn't mention any.
I don't know if you can make a perfusion pump fit into a shoebox, especially not without very good funding. I do remember a case where a standby team (With a slightly-more-than-briefcase-sized perfusion pump, I think it was this) was working on one of those resusci-anne dolls and they mishandled the pump, causing a whole mess:
... (read more)I will add one thing that the reporter didn‟t because he had left the room to photograph some of the other CUK members before he lost his light to the setting sun. And that is that the venous blood reservoir bag in the circuit of the ATP exploded due to a misplaced clamp. The reporter apparently missed
What about a fracture that severs the brain in several pieces?
Hooking up the nerves is still tricky, but we could probably figure it out.
Wouldn't this be tantamount to regrowing a transected spine? I'm not up-to-date on that area, but I don't think we can do that yet.
substantially better neuroscience
We have plenty of models of neurons and some of them imitate neurons very well.
Eugene Izhikevich simulated an entire human brain equivalent with his model and he saw some pretty interesting emergent behaviour (Granted, the anatomy had to be generated randomly at every iteration, so we still need better computers).
I cannot believe nobody has recommended David Zindell yet! His work is a masterpiece of transhumanist fiction.
His Requiem for Homo Sapiens series is preceded by a short story Shanidar, you should read it first to get a taste of what's next. If you want more, then the next four books are:
I'll second After Life, it's very short but definitely one of my favorite pieces of h+ fiction. The work of Cordwainer Smith (He only wrote a novel and a few short stories) could also be considered transhumanist fiction, as it includes... (read more)