The naïve way of understanding mind uploading is "we take the connectome of a brain, including synaptic connection weights and characters, and emulate it in a computer". However, people want their personalities to be uploaded, not just brains. That is more than just replicating the functionality of their brains in silico.
This nuance has lead to some misunderstandings, for example, to experts wondering [1] why on Earth would anyone think that brain-centredness [2] (the idea that brains are "sufficient" in some vague sense) is a necessary prerequisite for successful whole brain emulation. Of course, brain-centredness is not required for brain uploading to be technically successful; the problem is whether it is sufficient for... (read 776 more words →)
I agree with pragmatist (the OP) that this is a problem for the correspondence theory of truth.
Usefulness? Just don't say "experimental evidence". Don't oversimplify epistemic justification. There are many aspects - how well knowledge fits with existing models, with observations, what is it's predictive power, what is it's instrumental value (does it help to achieve one's goals) etc. For example, we don't have any experimental evidence that smoking causes cancer in humans, but we nevertheless believe that is does. The power of Bayesian approach is in the mechanism to fuse together all these different forms of evidence and to arrive at a single posterior probability.