You have already found the only published randomized trial of worms in MS (the JAMA neurology paper). If I were in your position, worms would not be the first option I would look into.
One meta-reason to be skeptical: one often sees worms touted as a solution for all autoimmune diseases. But therapies are not trivially transferable across autoimmune diseases. For example, anti-TNF therapies are effective in RA, but exacerbate MS; natalizumab is effective in MS, but exacerbates neuromyelitis optica. The latter case is especially shocking, as NMO is clinically nearly identical to MS, and was in fact considered a variant of MS for a long time. The biology is distinct across... (read 368 more words →)
You have already found the only published randomized trial of worms in MS (the JAMA neurology paper). If I were in your position, worms would not be the first option I would look into.
One meta-reason to be skeptical: one often sees worms touted as a solution for all autoimmune diseases. But therapies are not trivially transferable across autoimmune diseases. For example, anti-TNF therapies are effective in RA, but exacerbate MS; natalizumab is effective in MS, but exacerbates neuromyelitis optica. The latter case is especially shocking, as NMO is clinically nearly identical to MS, and was in fact considered a variant of MS for a long time. The biology is distinct across... (read 368 more words →)