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Are you afraid of dry eyes/meibomian gland dysfunction at all? It seems like it's pretty common as a side effect of retinoids.

sid-kap10

so that after 11 stacked 'equal-tempered' 5ths, each of them 1/50th of a semitone sharp, we arrive back at a perfect octave multiple of the original frequency.

Don't the 5ths need to be slightly flat (700 cents instead of 702 cents) to have the octaves in tune?