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aleksiL comments on Open Thread, June 16-30, 2013 - Less Wrong
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I'm pretty sure "trying to eat less" is exactly the wrong thing to do. Calorie restriction just triggers the starvation response which makes things worse in the long run.
Change what you eat, not how much.
I'm pretty sure "Force feeding yourself as much fat as you can keep down with the aid of anti-emetics, taking glucose intravenously while injecting insulin, estrogen and testosterone and taking a β2 antagonist" is closer to "exactly the wrong thing to do".
Physics is still relevant. The only way to lose weight (outside of surgery) is to spend more energy than you take in. The problem, of course, is that your energy intake and your energy output are functions of each other plus a lot of other things besides (including what's on your mind).
I still think that for most people (aka with an uninformative prior) the advice of "Eat less, move more" is a good starting point. Given more data, adjust as needed.
It's not that unusual for people to regain what they lost plus more after a failed diet.
I've replaced “eat less” with “lose weight” because I don't want to go into this, but see Lumifer's reply.