Introduction Brain energy is often confused with motivation, but these are two distinct phenomena. Brain energy is the actual metabolic energy available to the neurons, in the form of adenosine triphosphate (ATP) molecules. ATP is the "energy currency" of the cell, and is produced primarily by oxidative metabolism of energy...
Quantum immortality sounds exactly like the mythical hell: living forever in perpetual agony, unable to die and in your own branch of existence separate from everyone else you ever knew. What if we can hack quantum immortality to force continued good health, and the mutual survival of our loved ones...
Nutrition is a case where we have to try to make the best possible use of the data we have no matter how terrible, because we have to eat something now to sustain us while we plan and conduct more experiments. I want to apply Bayes theorem to make rational...
While I think finding ways to make future generations healthier and smarter is a worthy goal, I don't think we understand enough yet to do this without potentially severe unintended consequences, and I wouldn't consider doing it myself with our current technology. It's a good bet that many of the seemingly deleterious mutations we'd like to eliminate also offer some benefit we don't understand- given that we have already discovered many instances of mutations with apparent intelligence/health tradeoffs, and disease resistance/health tradeoffs. If you're selecting embryo populations for mutations correlated with specific desirable traits, you should also expect that you are selecting for worse outcomes in all other potentially desirable dimensions including... (read more)
Interesting, thanks for sharing. I am also on the west coast, and wear wide brimmed hats (usually cowboy hats), which is somewhat unusual and many of the people comment on it, complement it, or ask me about it.
The truth is, I'm not really trying to make a fashion statement, I'm just bald and don't want to get cancer on my head... and this hat design is uniquely functional in that it blocks the sun, doesn't blow off in the wind, and doesn't look incredibly dorky and non-breathable like the nylon sun hats they sell at REI. Yet people make a big deal about it and the social dynamics of peoples reactions are... (read more)
As someone that has been a strength athlete, and part of fitness communities for many years, I have never seen a real world instance of someone becoming generally less attractive to the opposite sex, or having trouble finding partners due to lifting weights.
Building noticeable amounts of muscle is much harder than most people who haven't tried to do so assume. The "grotesquely muscular" men on, e.g. bodybuilding magazines are essentially fake, and not something that really happens to people that lift weights, except for a few minutes in a staged photo that requires months of preparation. To get like that you need a combination of massive doses of steroids, weight training and... (read more)
Late reply I know, but I wanted to add that I was very surprised by your take on Brett Kavanaugh, and wanted to explain my more negative interpretation of those events, as I see it as very helpful to Trump directly, and not about principles. Some points:
-Backing down from anything almost always involves giving up political power, and encourages people to challenge you in the future. Trump is known for consistently almost never giving up without a fight, even in situations like losing an election. This strongly discourages people from challenging you in the future, because they know it will be a big fight, even if they win.
-His goal appears to have... (read more)
Growing crops for biofuel cannot produce more carbon than it consumes over long time scales, because the only source of carbon available to the system is the carbon in the atmosphere. If they are saying biofuels aren't carbon neutral over long time scales, where is this extra unlimited supply of carbon coming from?
High intensity deliberate practice that you can only do for short amounts of time per session
How is that different from flow work?
I'm not sure if you've read Mihály Csíkszentmihályi or not, but he argued that flow states are more likely when a task is more complex/challenging, and the person has a high level of appropriate skill that makes it possible (with substantial effort) to complete the task.
For me this often occurs while programming, sailing, or doing math- especially if I need to solve a new problem with those skills that will be especially challenging.
Once I'm in 'flow' it is a distinct mental experience - I am totally into it and lose any sense of time passing, or of needing to motivate myself until I am interrupted either by my own body, or by something external.
Cal Newport in Deep Work (his own word for flow work) defines "Deep Work" as anything that requires skills that would take at least a year to develop if a person was already generally educated, smart, and motivated.
I stopped using pomodoros for flow-work, because it would break my flow state. I've found roughly 2 hour chunks work better for flow, without any particular warning to stop me if I feel like going longer. If I am in flow, I want it to keep going as long as possible, until I am fatigued, or the problem is solved.
But I would have thought that if there was widespread 'central hypothyroidism', someone would have twigged by now, since that form does show up if you do a full panel of hormone tests
Which tests? I am not aware of any simple blood test that measures the endpoint of thyroid activity on metabolic rate (except, arguably, cholesterol levels), rather than just the state of the T4->TRH->TSH->T4 feedback loop.
mostly T4 with a bit of extra T3', but no-one has particularly clear ideas on what works and what doesn't or why
The challenge with T3 is it has a very short half-life, one would need to take very small doses impracticably often to achieve stable... (read more)
Brain energy is often confused with motivation, but these are two distinct phenomena. Brain energy is the actual metabolic energy available to the neurons, in the form of adenosine triphosphate (ATP) molecules. ATP is the "energy currency" of the cell, and is produced primarily by oxidative metabolism of energy from food. High motivation increases the use of this energy, but in the absence of sufficient metabolic capacity it eventually results in stress, depression, and burnout as seen in manic depression. Most attempts at cognitive enhancement only address the motivation side of the equation.
... (read 822 more words →)The “smart drug” culture has generally been thinking pharmaceutically rather than biologically. Behind that pharmaceutical orientation there is sometimes the
Quantum immortality sounds exactly like the mythical hell: living forever in perpetual agony, unable to die and in your own branch of existence separate from everyone else you ever knew.
What if we can hack quantum immortality to force continued good health, and the mutual survival of our loved ones in the same branch of the universe as us?
It seems like one would "simply" need a device which monitors your health with biosensors, and if anything goes out of range- it instantly kills you in a manner with extremely low probability of failure. All of your friends and family would wear a similar device, and they would be coupled such that if one... (read more)
Nutrition is a case where we have to try to make the best possible use of the data we have no matter how terrible, because we have to eat something now to sustain us while we plan and conduct more experiments.
I want to apply Bayes theorem to make rational health decisions from relatively weak data. I am generally wondering how one can synthesize historical human experiences with incomplete scientific data, in order to make risk-adverse and healthy decisions about human nutrition given limited research.
Example question/hypothesis: Does gluten cause health problems (ie exhibit chronic toxicity) in non-coeliac humans? Is there enough evidence to suggest that avoiding gluten might be a prudent risk-adverse decision... (read more)
As I mentioned, I do actually sometimes get negative feedback from people, but overall the effect is positive, because it causes people to interact with me spontaneously when I have trouble initiating social interactions, and I've made quite a few good friends just from that. Being polarizing is way better than being neutral for meeting people and making friends. I also suspect being avoided by a person that would negatively judge someone they don't know just for wearing a hat is probably also a positive thing. It's a functional thing I need because I'm bald with pale skin and spend a lot of time outdoors in a sunny climate, so people that... (read more)