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I have reservations about postulating "happiness" as some kind of metaphysical goal for humans. "Happiness" seems to have come about as an evolutionary spandrel, since unhappy humans can breed and keep the species in business just fine.
The implied teleology in Buddhist "enlightenment" also bothers me. Why would humans have the capacity for this experience? Again, it sounds like another spandrel.
Of course it is an evolutionary spandrel, but we don't necessarily need to choose our goals to have the same ones as those of the evolution machine.
But I think the important part is that there is a very fine line of unhappiness with which humans can still be effectively working on goals. Even a minor, unnoticed, undiagnosed, and generally invisible depression can easily make people significantly less motivated to work on anything. If you choose any goal, say, colonizing the galaxy, you probably need at the very least almost happy people to work effectivel... (read more)