(Nice interrobang.)

There's only something wrong with holding both "Pr(intelligent life in Milky Way) non-negligible" and "Pr(intelligent life in observable universe) not-almost-1" if the events "life in galaxy 1", "life in galaxy 2", etc., are independent or approximately so. So if you assign substantial probability to propositions like "intelligent life basically can't actually emerge naturally at all, but we were put here by a god" or "subtle variations in the laws of physics across the universe mean that our galaxy is suitable for intelligent life but most others aren't" then you can consistently give such answers.

I can't think of any reason for the right sort of intergalactic correlation that's likely to be thought probable by many LWers, though.